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Clear aligners vs. traditional braces: which fixes jaw problems better?

NCT ID NCT07454694

Disease control Sponsor: Bezmialem Vakif University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two treatments for Class II malocclusion (overbite) in 34 growing patients: clear aligners and Twinblock appliances. Researchers measured changes in jaw and teeth position using X-rays. The goal was to see if clear aligners could work as well as the traditional Twinblock for correcting jaw alignment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Invisalign Clear Aligners and Twinblock Functional Appliance
What this could lead to
If clear aligners work as well as Twinblock, patients may have a more comfortable, less visible option for correcting jaw alignment.
What could go wrong
This is a small, completed study with only 34 participants. Results may not apply to all patients, and clear aligners might not be as effective for severe cases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

34 people

The number who actually took part.

Started

Aug 2023

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

10 to 14 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with Angle Class II molar and canine relationship * Overjet greater than 6 mm * Patients in the growth spurt period Exclusion Criteria: * History of orthodontic treatment * Missing teeth * Patients in mixed dentition period * Systemic diseases affecting growth or bone metabolism

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Conditions

The condition(s) this trial relates to.

Overbite

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Class II malocclusion Mandibular retrognathism

Contacts and locations

Locations

  • Bezmialem Vakif University

    Istanbul, Fatih, 34093, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.