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Braces vs. aligners: which is safer for your tooth roots?

NCT ID NCT07236775

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 40 young adults (ages 18-25) with severely crowded teeth who needed four premolars removed. Researchers compared how much the tooth roots shortened after treatment with clear aligners versus traditional braces. They used 3D X-rays to measure root length before and after treatment. The goal was to see which method causes less root damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Nov 2019

Finished

Feb 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 25 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients aged 18-25 years. * Class I malocclusion with severe dental crowding. * Tooth size-arch discrepancy more than 6 mm. * No congenitally missing or extracted teeth (except for the wisdom teeth). * No history of previous trauma to the maxillofacial region or surgical interventions. Exclusion Criteria: * Previous orthodontic treatment. * Presence of previously occurred ARR. * Patients with psychological abnormalities or systemic diseases. * Patients with known allergies to latex or plastic materials.

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Conditions

The condition(s) this trial relates to.

Malocclusion

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Orthodontics, Faculty of Dentistry, University of Damascus

    Damascus, Syria

More trials for these conditions

Other studies related to the condition(s) this trial covers.