Brain scans reveal hidden blood vessel damage in early Alzheimer's
NCT ID NCT06322121
First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 40 times
Summary
This study uses special MRI scans to track changes in blood vessel function in the brains of 120 people with early Alzheimer's or mild memory problems, as well as healthy volunteers. The goal is to understand how small blood vessel disease, like cerebral amyloid angiopathy, contributes to dementia over time. By measuring how blood vessels react to visual stimulation, researchers hope to find early signs of damage that could lead to better treatments in the future.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Leids Universitair Medisch Centrum
Leiden, 2333 ZA, Netherlands
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help identify early markers of blood vessel damage in Alzheimer's, paving the way for future treatments that target these vascular issues.
What could go wrong
This is an observational study, not a treatment trial. It may not directly lead to new therapies, and the findings might not apply to all dementia patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.