Supplement and exercise combo tested in older women
NCT ID NCT07143305
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This small pilot study looked at whether taking citrulline malate (a supplement) along with a regular exercise program could improve physical function and health markers in active women aged 60-75. Twenty women completed the 12-week program, which included strength, balance, and walking tests, plus blood tests. The goal was to see if the supplement could enhance the benefits of exercise, but results are still being analyzed.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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20 people
The number who actually took part.
- Started
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Mar 2020
- Finished
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May 2020
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 to 75 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Each participant underwent a comprehensive medical evaluation by their primary care physician to confirm their health status and eligibility. Inclusion criteria: * Sex: women. * Age: 60-75 years. Exclusion criteria: * Functional limitations (Barthel Index \<100 and/or Lawton-Brody Scale \<8). * Musculoskeletal injuries within the past six months. * Cardiovascular disease (e.g. advanced heart failure, unstable angina, recent myocardial infarction, arrhythmias, uncontrolled hypertension or hypotension, aortic stenosis, thromboembolic events). * Respiratory disorders (e.g. chronic respiratory failure or a moderate/severe BODEx index). * Endocrine/metabolic diseases (e.g. uncontrolled diabetes). * Neurological or psychiatric disorders (e.g. dementia). * Prior use of ergogenic nutritional supplements. * Any other condition deemed incompatible with moderate physical activity by the clinical team.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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City Council of Soria
Soria, Spain
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