New computer tool aims to boost cirrhosis care in hospitals
NCT ID NCT05967273
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests a computer program called CirrhosisRx that helps doctors follow national guidelines when treating hospitalized patients with cirrhosis. The tool organizes patient data and suggests appropriate orders. Researchers will compare care quality and patient outcomes between hospitals using the tool and those using usual care. About 2,100 adults with cirrhosis are being enrolled.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- CirrhosisRx clinical decision support system (a computer tool that organizes patient data and suggests guideline-based orders)
- What this could lead to
- If it works, this tool could help doctors provide more consistent, guideline-based care for hospitalized cirrhosis patients, potentially reducing complications and deaths.
- What could go wrong
- This is a pragmatic trial testing a decision-support tool, not a new drug or cure. The tool may not change outcomes if doctors don't use it or if other factors limit its impact.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 2,106 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2025
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * All adult (age ≥ 18 years) patients who have cirrhosis identified based on 1+ chronic liver disease and 1+ cirrhosis (or its complications) International Classification of Diseases, Revision 10 diagnosis codes OR mention of cirrhosis or portal hypertension (or their complications) in clinical documentation admitted at our institution. Exclusion Criteria: * Children (age \< 18 years) * patients who do not meet the cirrhosis definition criteria as noted above * ambulatory patients
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of California San Francisco Medical Center
RECRUITINGSan Francisco, California, 94143, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Sound waves may replace the needle in liver scarring tests
- Ultrasound may replace invasive test for dangerous liver complication
- Could a wearable zapper quiet cirrhosis pain without drugs?
- A needle through the gut could replace the standard liver pressure test
- Can two experimental drugs be used safely in people with cirrhosis?
- Can bedside ultrasound guide fluid treatment for cirrhosis patients?