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Exercise circuit shows promise for insulin resistance

NCT ID NCT04528693

Disease control Sponsor: Poznan University of Physical Education Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether 12 weeks of circuit training (combining strength and endurance exercises) could improve insulin sensitivity and blood vessel function in women with insulin resistance. Forty-nine women aged 25-45 participated, with some doing the circuit training three times a week and others serving as a control group. Researchers measured changes in insulin resistance, blood sugar, cholesterol, and other health markers.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
circuit training (strength and endurance exercises)
What this could lead to
If it works, this could point toward a non-drug way to help manage insulin resistance and improve heart health.
What could go wrong
This is a small, completed study with only 49 women, so results may not apply to everyone. Exercise programs also require long-term commitment to maintain benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

49 people

The number who actually took part.

Started

Aug 2020

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 45 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * women, * age: 25-45years, * menstruating, * BMI 18,5-29,9 kg/m2, * insulin resistance based on HOMA -IR (cut-off point 2.5), * not contraindicated to physical activity. Exclusion Criteria: * type 1 and 2 diabetes, * poorly controlled hypertension (mean SBP \>140mmHg and/or mean DBP \>90mmHg) over the last month and/or need to modify the pharmacological treatment, * obesity: BMI \> 30 kg/m2, * lipid disorders requiring implementation of pharmacological treatment in the last 3 months before or during observation, * a positive history of ischemic heart disease, carotid atherosclerosis and / or lower limb atherosclerosis, * clinically significant arrhythmias or conduction disorders, * chronickidney disease, * clinically significant liver dysfunction, * acute or chronic, clinically manifest inflammatory process, * an acute infection in the last month, * cancer, * taking dietary supplements within a month before inclusion and during observation, * taking medication that could interfere with the results of the tests, * other conditions that may pose any risk to the patient during the observation.

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Conditions

The condition(s) this trial relates to.

Back Pain Inflammation Insulin Resistance

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Insulin resistance

Contacts and locations

Locations

  • Poznan University of Physical Education

    Poznan, 61-871, Poland

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