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New study aims to make anesthesia safer for seniors

NCT ID NCT07301242

Knowledge-focused Sponsor: Shanghai Geriatric Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study at Shanghai Geriatric Medical Center looks at how the anesthetic drug ciprofol behaves in 50 older adults (65+) undergoing limb surgery. Researchers will collect blood samples and monitor vital signs to build a model that could help doctors adjust doses more precisely. The goal is to improve safety and recovery for elderly patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ciprofol (an intravenous anesthetic)
What this could lead to
If successful, this could help doctors give more precise and safer doses of ciprofol to older patients during surgery.
What could go wrong
This is a small, early observational study with only 50 participants, so results may not apply to all older adults. It is not testing a new treatment, just gathering data.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Elderly patients undergoing orthopedic limb surgery

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥65 years; * BMI: 18-30 kg/m²; * ASA physical status classification I-III; * Scheduled for elective orthopedic limb surgery under general anesthesia; * Expected duration of surgery \>30 minutes; * Willing to participate and able to provide written informed consent. Exclusion Criteria: * Known allergy to ciprofol or related medications, or any contraindication to their use; * Preoperative cognitive impairment; * History of severe cerebrovascular disease or related complications; * History of neuromuscular system diseases or psychiatric disorders; * History of sedative medication use; * History of alcohol abuse or substance use disorder; * Bradycardia (heart rate \<60 beats per minute); * Hypotension (mean arterial pressure \<55 mmHg); * QT interval prolongation; * Uncooperative or unable to communicate effectively.

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Conditions

The condition(s) this trial relates to.

femoral neck fracture hip fracture osteoarthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Femoral neck fractures Hip fractures (icd-10 72.01-72.2) Osteoarthritis, knee and hip

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Shanghai Geriatric Medical Center

    RECRUITING

    Shanghai, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.