Can a nerve block stop pain months after hysterectomy?
NCT ID NCT07830706
First seen Sep 21, 2026 · Last updated Sep 21, 2026
Summary
Researchers are testing whether an erector spinae plane block, a nerve block given before abdominal hysterectomy, can reduce pain after surgery and prevent chronic and neuropathic pain. Adults scheduled for the procedure receive either the block with bupivacaine or standard pain management without it. The team measures pain in the early postoperative period and again at 1 and 6 months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bupivacaine, a local anesthetic injected around the spinal nerves as part of an erector spinae plane block
- What this could lead to
- If the block works, it could give surgeons a targeted way to reduce pain after abdominal hysterectomy and lower the chance of chronic pain months later.
- What could go wrong
- This is a single-center study of 200 patients, so results may not apply everywhere. Nerve blocks can fail, wear off, or cause temporary weakness, and chronic pain has many causes beyond surgery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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200 people
The number who actually took part.
- Started
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Jan 2025
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria Adults aged 18-65 years American Society of Anesthesiologists (ASA) physical status I-III Body mass index (BMI) \<35 kg/m² Scheduled for elective total abdominal hysterectomy under general anesthesia Provided informed consent to participate in the study Exclusion Criteria Decompensated heart failure Severe respiratory distress Renal failure Hepatic failure History of opioid addiction Current anticoagulant use or bleeding diathesis Refusal to participate in the study \-
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Necmettin Erbakan University Medical Faculty Hospital Konya, Türkiye
Konya, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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