Hidden inflammation lingers after urethritis, new study suggests
NCT ID NCT01732172
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study checks if men who had a treated urethritis infection still have signs of long-term inflammation and cell damage in their genital tract. Researchers measured a protein called elastase and markers of oxidative stress in semen 6 and 12 months after treatment. They compared 113 men who had urethritis with healthy men who never had a genital infection.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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113 people
The number who actually took part.
- Started
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Dec 2012
- Finished
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Feb 2016
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria common to both groups: * Subjects aged 18 and over * Voluntary and signed informed consent Inclusion criteria specific to the group "patient": * Patients with clinical signs of urethritis / or * Patients treated for urethritis following the usual protocols in the month before inclusionand / or * Patients with positive chlamydial research, or Mycoplasma genitallium or Garderella vaginalis or gonorrhea in the sperm or first urinary stream; Inclusion criteria specific to the group "control": \- Patients with no urethritis or no history of urogenital infection Exclusion criteria common to both groups: * Subjects not wishing to participate in the study * Subjects that have not signed the informed consent * Those not affiliated to the social security system (or entitled beneficiary) * Immunodepressed or have an infection associated with HIV, HBV or HCV * Chronic systemic disease Exclusion criteria specific to the group "patient": \- Patients with no signs of urethritis Exclusion criteria specific to the group "control": \- Subjects with signs of urethritis
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hospital Cochin
Paris, 75014, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.