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Scientists track immune changes in 9 volunteers stranded on Sub-Antarctic island for a year

NCT ID NCT07275489

Knowledge-focused Sponsor: University Hospital, Angers Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 9 healthy young adults living for one year on the remote Kerguelen Islands to see how extreme isolation and stress affect their immune system. Researchers will collect blood, saliva, stool, urine, and hair samples every three months to measure immune cells, stress hormones, gut bacteria, and dormant virus reactivation. The goal is to understand how the body adapts to long-term confinement, which could help people with chronic illnesses or those in isolated environments like space missions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could reveal how stress and isolation weaken immunity, potentially guiding ways to support immune health in chronically ill or isolated people.
What could go wrong
This is a very small observational study (9 people) in a unique environment, so findings may not apply to the general population. It collects samples but does not test any treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 9 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participant included in the CELREMED research project of the University Hospital of Angers on helathy volunteers in the context of CHOICE Kerguelen 1 protocol

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria : * healthy people aged \> 18 years * Participant affiliated with or benefiting from a social security system * Participant has signed informed consent * Participant staying as an overwintering member at Kerguelen from November 2025 to November 2026 * Participant included in the CELREMED research project of the University Hospital of Angers on helathy volunteers in the context of CHOICE Kerguelen 1 protocol Exclusion Criteria: * age \< 18 years * Pregnant, breastfeeding, or postpartum woman * immunocompromised people (primary immunodeficiency, HIV infection or immunosupressive treatment) * Person refusing to participate in the study * Person with a history of autoimmune disease - -Person deprived of liberty by judicial or administrative decision * Person undergoing involuntary psychiatric treatment * Person subject to a legal protection measure

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Human health in extreme conditions

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hôpital SAMUKER, Port-aux-français/ Archipel KERGUELEN /Terres Australes et Antarctiques Françaises

    RECRUITING

    Port-aux-Français, Terres Australes Et Antarctiques Françaises, French Southern and Antarctic Lands

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