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Spine adjustments tested for Post-Concussion relief

NCT ID NCT06151184

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This small, early-stage trial looked at whether chiropractic adjustments could affect how the nervous system works in people with post-concussion syndrome. Only 3 people were enrolled before the study ended. Researchers measured brain activity, heart signals, and walking patterns before, during, and after 6 weeks of chiropractic care. The goal was to see if the approach is worth studying further, not to prove it works.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
chiropractic adjustment
What this could lead to
If this works, it could point toward a non-drug way to help people with lingering concussion symptoms.
What could go wrong
This is a very small, early proof-of-concept trial (only 3 participants enrolled) that was terminated. It cannot prove effectiveness, only test if the approach is feasible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

3 people

The number who actually took part.

Started

Jan 2024

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18 or older * Diagnosed by a physician with post-concussion syndrome OR self-identifies as having a concussion based on responses to the HELPS screening tool * Has at least 3 of the following chronic symptoms at least 3 months since concussion: headache; dizziness; insomnia; fatigue; concentration difficulty; memory difficulty; intolerance to stress, emotions, and alcohol; irritability * Able to understand and communicate in English * Able to make informed decisions without assistance * Can wear an EEG net for 40 minutes * Can sit quietly for at least 15 minutes * Capable of walking on a treadmill at a comfortable pace for 10 minutes consecutively * Capable of moving from a supine to standing to supine position quickly and safely * Able to wear multiple electrodes placed on chest, back, and fingertips * Able to wear multiple sensors placed on head, back, pelvis, hands, arms, and legs * Has not had a chiropractic adjustment within the last one month * Has not received any other interventions within the past one month such as osteopathic spinal manipulation, physical therapy rehabilitation or manipulation, massage, body movement therapies, or acupuncture Exclusion Criteria: * Diagnosed with a serious mental disorder such as schizophrenia or bipolar disorder * Has malignant hypertension, which is a condition whereby their blood pressure rises suddenly and quickly * Has a known condition that causes syncope with postural changes, such as POTS * Has an implanted device (i.e., pacemaker) * Has a physical disability affecting their gait * Has a history of previous surgery or injury to the musculoskeletal structures or skull in the past three months * Has a prosthetic for any extremity * Has a hearing impairment or uses a hearing aid * History of stroke * Taking short-acting benzodiazepines, which includes midazolam and triazolam * Involved with current litigation related to a physical health-related injury * Untreated diagnosed osteoporosis or articular instability such as atlanto-axial instability * Currently pregnant * Unwilling to wash hair/head and remove hair products, accessories, braids, or wigs for assessment appointments * Deemed high-risk using the Columbia-Suicide Severity Rating Scale (C-SSRS) and referred for further evaluation (assessed at initial session in lab) * Experiences daily/chronic pain \>3 out of 10 on the visual analog scale (VAS)

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Conditions

The condition(s) this trial relates to.

Post-Concussion Syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dr. Sid E. Williams Center for Chiropractic Research

    Marietta, Georgia, 30067, United States

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Other studies related to the condition(s) this trial covers.