Herbal hope: can ancient medicine stop lung Cancer's return?
NCT ID NCT05834413
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether adding Chinese herbal medicine to standard chemotherapy and immunotherapy can help prevent lung cancer from coming back after surgery. About 367 adults with a certain type of lung cancer (driver gene negative, stage Ib to IIIb) will take part. The goal is to see if the herbs improve how long people stay cancer-free and their quality of life.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 367 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2023
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 74 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patients who underwent complete surgical resection (R0) with postoperative pathology confirmed as stage Ib to IIIb non-small cell lung cancer. 2. Patients whose tissue or blood specimens tested negative for driver genes. 3. Patients who received their first chemotherapy within 8 weeks postoperatively. 4. Age ≥ 18 years ≤ 74 years, regardless of gender. 5. Eastern Cooperative Oncology Group performance status (ECOG PS) ≤ 2 points. 6. absolute neutrophil value \>1.5×109 /L, platelet count \>80×109 /L, hemoglobin \>90mg/dL; no abnormal liver and kidney function test results. 7. Understand and agree to participate in this study and sign the informed consent form. Exclusion Criteria: 1. Having unresectable or metastatic disease, pathology reports without a clear pathological diagnosis, showing the presence of residual lesions at the microscopic surgical margins, and surgical residual lesions. 2. Any medical condition with a life expectancy of less than 5 years, except for risk of recurrent lung cancer. 3. Current malignant disease or history of malignant disease (except resected NSCLC), combined with serious diseases of the heart, liver, kidney and hematopoietic system, diagnosed and/or requiring treatment within the past three years. 4. With a history of psychiatric disorders that are not easily controlled. 5. Patients who are pregnant or lactating. 6. Patients who are allergic to therapeutic drugs.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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YueYang Hosptial of Intergrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine
RECRUITINGShanghai, Shanghai Municipality, 200437, China
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