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10,000 headache patients join landmark registry study

NCT ID NCT05334927

Knowledge-focused Sponsor: Beijing Tiantan Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study is collecting information from 10,000 people aged 12 and older with common headache disorders like migraine and tension-type headaches. Researchers will track their symptoms, brain scans, genetics, and thinking abilities over time. The goal is to better understand these conditions and improve future treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 10,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2022

Expected to finish

Dec 2032

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients diagnosed with primary headache (migraine, tension headache and other types of primary headache) or primary headache complicated with MOH according to ICHD-3.

Ages

12 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age ≥ 12 years old,Any gender; 2. The first onset age of primary headache was less than 50 years old(Age \<65 years at first diagnosis of chronic migraine); 3. patients with primary headache (migraine, tension headache and other types of primary headache) or primary headache complicated with MOH according to ICHD-3; 4. Sign the informed consent form. Exclusion Criteria: 1. According to the ICHD-3 diagnostic criteria, there are still headaches directly related to secondary factors (except drug overuse) at the time of enrollment; 2. Those who cannot be diagnosed as primary headache or primary headache combined with medication overuse headache according to ICHD-3; 3. According to DSM-V diagnostic criteria, patients with severe mental diseases (such as schizophrenia, mental disorders associated with mental retardation, etc.); 4. Patients with severe organic diseases, such as malignant tumors, and the expected survival time is less than 1 year; 5. Pregnant,planning pregnancy or Lactating women; 6. Subjects participating in other clinical trials; 7. Unable to cooperate to complete the follow-up due to geographical or other reasons

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Conditions

The condition(s) this trial relates to.

headache disorder Headache Disorders, Secondary hypnic headache migraine disorder Tension-Type Headache trigeminal autonomic cephalalgia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Headache disorders, primary Medication overuse headache Migraine New daily persistent headache Tension-type headache Trigeminal autonomic cephalalgia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    61 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Anqing Municipal Hospital

    RECRUITING

    Anqing, Anhui, China

  • Ansteel Group General Hospital

    RECRUITING

    Anshan, Liaoning, China

  • Baotou Central Hospital

    RECRUITING

    Baotou, Inner Mongolia, China

  • Beijing Chaoyang Hospital

    RECRUITING

    Beijing, Beijing Municipality, China

  • Beijing Tiantan Hospital, Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, 100070, China

  • Brain Hospital Affiliated to Nanjing Medical University

    RECRUITING

    Nanjing, Jiangsu, China

  • Changzhou First People's Hospital

    RECRUITING

    Changzhou, Jiangsu, China

  • Chengdu Second People's Hospital

    RECRUITING

    Chengdu, Sichuan, China

  • Chongqing People's Hospital

    RECRUITING

    Chongqing, Chongqing Municipality, China

  • Dachuan District People's Hospital

    RECRUITING

    Dazhou, Sichuan, China

  • Deyang People's Hospital

    RECRUITING

    Deyang, Sichuan, China

  • Fujian Provincial Hospital

    RECRUITING

    Fuzhou, Fujian, China

  • Guangyuan Hospital of Traditional Chinese Medicin

    RECRUITING

    Guangyuan, Sichuan, China

  • Hospital of Chengdu University of Traditional Chinese Medicine

    RECRUITING

    Chengdu, Sichuan, China

  • Huludao Central Hospital

    RECRUITING

    Huludao, Liaoning, China

  • Huzhou Central Hospital

    RECRUITING

    Huzhou, Zhejiang, China

  • Jiujiang First People's Hospital

    RECRUITING

    Jiujiang, Jiangxi, China

  • Luohe Central Hospital

    RECRUITING

    Luohe, Henan, China

  • Luoyang Central Hospital

    RECRUITING

    Luoyang, Henan, China

  • Nanchong Central Hospital

    RECRUITING

    Nanchong, Sichuan, China

  • Panzhihua Central Hospital

    RECRUITING

    Panzhihua, Sichuan, China

  • Peking University Third Hospital

    RECRUITING

    Beijing, Beijing Municipality, China

  • Qinghe County People's Hospital

    RECRUITING

    Xingtai, Hebei, China

  • Qinhuangdao Haigang Hospital

    RECRUITING

    Qinhuangdao, Hebei, China

  • Ruijin-Hainan Hospital Shanghai Jiao Tong University School Of Medicine

    RECRUITING

    Qionghai, Hainan, China

  • Shandong Provincial Hospital

    RECRUITING

    Jinan, Shandong, China

  • Shandong Provincial Qianfoshan Hospital

    RECRUITING

    Jinan, Shandong, China

  • Shanghai Jiao Tong University School of Medicine Affiliated Tongren Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, China

  • Shenzhen Second People's Hospital

    RECRUITING

    Shenzhen, Guangdong, China

  • Siyang Hospital

    RECRUITING

    Siyang, Sichuan, China

  • The 7th People's Hospital of Zhengzhou

    RECRUITING

    Zhengzhou, Henan, China

  • The First Affiliated Hospital of Guangxi University of Chinese Medicine

    RECRUITING

    Nanning, Guangxi, China

  • The First Affiliated Hospital of Hebei North University

    RECRUITING

    Zhangjiakou, Hebei, China

  • The First Affiliated Hospital of Nanchang University

    RECRUITING

    Nanchang, Jiangxi, China

  • The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital)

    RECRUITING

    Wuhu, Anhui, China

  • The First Affiliated Hospital of Wenzhou Medical University

    RECRUITING

    Wenzhou, Zhejiang, China

  • The First Affiliated Hospital of Xiamen University

    RECRUITING

    Xiamen, Fujian, China

  • The First Affiliated Hospital of Zhengzhou University

    RECRUITING

    Zhengzhou, Henan, China

  • The First Hospital of Fangshan District, Beijing

    RECRUITING

    Beijing, Beijing Municipality, China

  • The First Hospital of Jilin University

    RECRUITING

    Changchun, Jilin, China

  • The First People's Hospital of Guangyuan

    RECRUITING

    Guangyuan, Sichuan, China

  • The First People's Hospital of Zunyi

    RECRUITING

    Zunyi, Guizhou, China

  • The Second Affiliated Hospital of Guangxi Medical University

    RECRUITING

    Nanning, Guangxi, China

  • The Second Affiliated Hospital of Harbin Medical University

    RECRUITING

    Harbin, Heilongjiang, China

  • The Second Affiliated Hospital of Henan University of Science and Technology

    RECRUITING

    Luoyang, Henan, China

  • The Second Affiliated Hospital of Xiamen Medical College

    RECRUITING

    Xiamen, Fujian, China

  • The Second Affiliated Hospital of Zhejiang University School of Medicine

    RECRUITING

    Hangzhou, Zhejiang, China

  • The Second Hospital of Jilin University

    RECRUITING

    Changchun, Jilin, China

  • The Second Hospital of Lanzhou University

    RECRUITING

    Lanzhou, Gansu, China

  • The Second Hospital of Shanxi Medical University

    RECRUITING

    Taiyuan, Shanxi, China

  • The Second People's Hospital of Guiyang

    RECRUITING

    Guiyang, Guizhou, China

  • The Third Affiliated Hospital of Chongqing Medical University

    RECRUITING

    Chongqing, Chongqing Municipality, China

  • Xinjiang Production and Construction Corps Hospital

    RECRUITING

    Ürümqi, Xinjiang, China

  • Xuchang Central Hospital

    RECRUITING

    Xuchang, Henan, China

  • Yangyuan County People's Hospital

    RECRUITING

    Zhangjiakou, Hebei, China

  • Yiyang County People's Hospital

    RECRUITING

    Luoyang, Henan, China

  • Zhangjiakou First Hospital

    RECRUITING

    Zhangjiakou, Hebei, China

  • Zhengzhou Central Hospital

    RECRUITING

    Zhengzhou, Henan, China

  • Zhongnan Hospital of Wuhan University

    RECRUITING

    Wuhan, Hebei, China

  • Zibo Municipal Hospital

    RECRUITING

    Zibo, Shandong, China

  • Zigong First People's Hospital

    RECRUITING

    Zigong, Sichuan, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.