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Brain scans reveal why some kids overeat

NCT ID NCT07266506

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how children's eating behaviors, like eating quickly or eating large portions, are linked to brain activity and body fat. Researchers will follow 420 children aged 7 to 9 for one year, using brain scans and meal observations. The goal is to understand why some kids are more likely to gain weight, which could help create better prevention strategies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 420 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Jun 2032

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

7 to 9 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Children : * Children must be of good health (with the exception of obesity being allowed) based on parental self-report. * Children should have no learning disabilities or developmental delays (e.g., ADHD, Autism, dyslexia) * Children should speak English fluently. * Children should not be on any medications known to influence body weight, taste, food intake, behavior, or blood flow, not be claustrophobic. * Children should between the ages of 7-9 years-old at enrollment. * Children must have a BMI-for-age % \< 85 or ≥ 95 to be enrolled. * The biological mother must have a BMI between 18.5 - 25.0 kg/m2 or a BMI ≥ 30.0 kg/m2. The parent primarily in charge of feeding must be able to accompany children to the visits. Parents : * The biological mother must have a BMI between 18.5 - 25.0 kg/m2 or a BMI ≥ 30.0 kg/m2. The parent primarily in charge of feeding must be able to accompany children to the visits. * The parent who has the most knowledge of the child's eating behavior, media access, sleep and behavior must be available to attend the visits with their child. This would be decided among the parents. Exclusion Criteria: Children : * They are not within the age requirements (\< 7 years-old or \> 9 years-old) at baseline. * They are taking cold or allergy medication, or other medications known to influence cognitive function, taste, appetite, or blood flow. * They are red/green colorblind. * They do not speak English fluently. * They report being claustrophobic, or if they have any of the following: a learning disability, ADD/ADHD, language delays, autism, dyslexia, a pre-existing medical condition such as type I or type II diabetes, rheumatoid arthritis, Cushing's syndrome, Down's syndrome, food allergies, severe lactose intolerance, Prader-Willi syndrome, HIV, cancer, renal failure, or cerebral palsy. * They have tattoos, permanent makeup, dental ware, pacemakers, or metal implants that would preclude safe completion of the MRI. * They have received an X-ray in the previous month. * Their BMI-for-age percentile is between 85-95th Parents : * The biological mother has a body mass index \< 18.5 kg/m2 or between 25-29.9 kg/m2. * The primary parent in charge of making feeding decisions is unable to attend the study visits. * The family reports plans to move away from the area in the next year.

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Conditions

The condition(s) this trial relates to.

Feeding Behavior Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Metabolic Kitchen and Children's Eating Behavior Lab

    State College, Pennsylvania, 16802, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.