Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Chew on this: dental rehab may sharpen aging brains

NCT ID NCT04458207

Knowledge-focused Sponsor: Folktandvården Stockholms län AB Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether restoring chewing ability through dental procedures can improve memory and thinking in adults aged 65-80. Eighty participants with chewing problems will be randomly assigned to receive dental rehabilitation either immediately or after a waiting period. Researchers will measure changes in memory tests before and after treatment to see if better chewing leads to better brain function.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Oral prosthetic rehabilitation (dental procedures including implants, dentures, and other treatments to restore chewing function)
What this could lead to
If it works, this could show that improving chewing ability helps maintain or improve memory and thinking in older adults, pointing toward a simple way to support brain health.
What could go wrong
This is a small, early-stage study (80 people) testing a cause-effect link, not a treatment for dementia. Results may not apply to everyone, and the intervention is dental care, not a drug or cure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2018

Expected to finish

Dec 2030

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 65-80 years of age at start * Impaired chewing ability (Eichner index B2-B4, C1-C4) * Dental rehabilitation with fixed prosthodontics, implant and/or tooth supported (overdentures included) \>10 occluding units * Mini Mental State Examination (MMSE) score \>25 Exclusion Criteria: * Brain trauma or stroke \<6 months * Neurological disease (stroke, dementia, Alzheimer disease, Parkinson disease). * Intellectual disability * Psychological disorders * Participants with chronic pain, depression or sleeping disorders * Daily analgesic medication that may affect cognitive and/or executive performance of the brain * Poor Swedish language skills, reading disabilities * Severely reduced hearing or vision * Prosthetic treatment with removable dentures (full or partial) MRI exclusion criteria: * Claustrophobia * Difficulties in lying down in a supine position for about an hour, or any other difficulties related to the MRI head coil * Participants with metal or medical implants in the body contraindicating MRI scan

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Chewing problem are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Cognition Disorders cognitive disorder Cognitive Dysfunction dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chewing problem Cognitive decline Degenerative; dementia Magnetic resonance imaging Mastication disorder Neurocognitive dysfunction

Contacts and locations

Locations

  • Eastmaninsitutet, Department of Prosthodontics

    Stockholm, 11324, Sweden

  • Eastmaninstitutet Folktandvården Stockholm AB

    Stockholm, Stockholm County, 11324, Sweden

More trials for these conditions

Other studies related to the condition(s) this trial covers.