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Chewing gum may skew asthma test results, study warns

NCT ID NCT07053956

Knowledge-focused Sponsor: RWTH Aachen University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether chewing gum changes a key asthma breath test called FeNO. Researchers had 30 adults with asthma chew a special sugar-free gum for 15 minutes and then measured their FeNO levels. The goal was to see if gum could cause wrong readings that might lead to incorrect treatment decisions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Aug 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. have known bronchial asthma with a FeNO level ≥25 ppb at regular medical checkups 2. are of legal age 3. are mentally and physically capable of understanding the significance and scope of the study and obeying the instructions of study personnel 4. are legally competent and have signed the informed consent form. Exclusion Criteria: 1. Current or past medically relevant illness or treatment that could impact the evaluability of the study. 2. FeNO levels \< 25 ppb 3. Medical contraindications to conducting FeNO measurements 4. Expected unwillingness to actively participate in study-related measures. 5. Known allergies or intolerances to the contents of chewing gum 6. Smoking, alcohol consumption, mouthwash use, chewing gum/candy/lettuce/spinach/kale/beetroot/radish/sausage consumption, or exercise on the day of the study.

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Conditions

The condition(s) this trial relates to.

asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Asthma bronchiale Chewing gum FENO

Contacts and locations

Locations

  • Department of Pneumology and Intensive Care Medicine, RWTH Aachen University Hospital

    Aachen, North Rhine-Westphalia, 52074, Germany

  • University Hospital Aachen

    Aachen, Aachen, 52074, Germany

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