Could chemo before surgery beat surgery alone for rare kidney cancer?
NCT ID NCT07155044
First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 40 times
Summary
This study compares giving chemotherapy before surgery versus surgery alone for patients with a rare cancer of the upper urinary tract. About 120 participants will receive either 3-4 cycles of gemcitabine and cisplatin followed by surgery, or surgery right away. The goal is to see if the chemo-surgery approach leads to better cancer control and survival.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
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Locations
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Changhai Hospital
Shanghai, Shanghai Municipality, 200090, China
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
gemcitabine and cisplatin (chemotherapy)
What this could lead to
If successful, this could show that giving chemotherapy before surgery helps control the cancer better and improves survival for patients with upper tract urothelial carcinoma.
What could go wrong
This is a small, non-randomized study at a single center, so results may not apply broadly. Chemotherapy has side effects like kidney damage and low blood counts, and it may not improve outcomes compared to surgery alone.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.