Could chemo before surgery beat cancer better?
NCT ID NCT07155044
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study compares giving chemotherapy before surgery versus surgery alone for patients with upper tract urothelial cancer. About 120 participants will be assigned to one of two groups based on their choice and doctor's evaluation. The goal is to see if the chemo-surgery combo leads to better tumor shrinkage and longer survival.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- gemcitabine and cisplatin (chemotherapy)
- What this could lead to
- If it works, this could show that giving chemotherapy before surgery helps shrink tumors and improve survival for people with upper tract urothelial cancer.
- What could go wrong
- This is a small, non-randomized study at one hospital, so results may not apply to everyone. Chemotherapy has side effects like kidney damage and low blood counts.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Changhai Hospital
Shanghai, Shanghai Municipality, 200090, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.