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Peel vs laser: which skin fix wins?

NCT ID NCT07036302

Symptom relief Sponsor: Jose Roberto Cortelli Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two common cosmetic treatments—chemical peels using trichloroacetic acid (TCA) and fractional lasers—for improving melasma, acne scars, and wrinkles. About 120 adults will receive three sessions of one treatment, and researchers will measure skin changes, satisfaction, and quality of life. The goal is to find which approach works best and is most comfortable for patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
trichloroacetic acid (TCA) chemical peel and fractional laser (Erbium-YAG and Neodymium-YAG)
What this could lead to
If successful, this could help doctors choose the most effective and comfortable skin-resurfacing treatment for melasma, acne scars, and wrinkles.
What could go wrong
This is a small, early-stage comparison study. Results may not apply to all skin types or guarantee long-term improvement. Risks include pain, scarring, and uneven skin tone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Men or women * aged 18 or over * acne scars, melasma or clear signs of photoaging and evident wrinkles * participants with acne scars or melasma will be included if they have never undergone treatment or if previous treatment has been ineffective. Exclusion Criteria: * phototype VI * autoimmune and dermatological diseases * known allergies to the components of the formulations * patients who prefer other treatment options * history of keloids * pregnant women * breastfeeding women * women of childbearing age who do not adopt a valid method of contraception

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Conditions

The condition(s) this trial relates to.

Hypertrophy Melanosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acne scars - mixed atrophic and hypertrophic Melasma Rejuvenation Resurfacing

Contacts and locations

Locations

  • Cavalca & Cortelli Research Center

    Taubaté, São Paulo, 12010-700, Brazil

  • University of Taubate Dental School

    Taubaté, São Paulo, 12020-330, Brazil

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