Can a chatbot make clinical trial consent clearer?
NCT ID NCT07756515
First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time
Summary
This study tests whether a chatbot called CoCo can help people understand what they're agreeing to when they join a clinical trial. Researchers want to see if using the chatbot is practical and if it improves comprehension and satisfaction compared to standard remote consent methods. The study involves 100 English-speaking adults who are being considered for enrollment in other research studies.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- CoCo Chatbot, a patient-facing chatbot designed to obtain informed consent
- What this could lead to
- If successful, this could make informed consent clearer and more satisfying for patients, potentially improving how clinical trials communicate with participants.
- What could go wrong
- This is a small feasibility study, so results may not apply broadly. The chatbot may not improve comprehension or satisfaction, and there could be technical or usability issues.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2027
An estimate. Start dates often move.
- Expected to finish
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Dec 2031
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Ability to understand and willingness to provide informed consent. * Age ≥18 years. * Patients whose preferred language is English. * Patients who are being considered for enrollment in selected clinical research studies. Phase I will be initiated using the Clearinghouse protocol PA11-0852, a non-interventional biomarker study. Exclusion Criteria: N/A
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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UT MD Anderson
Houston, Texas, 77030, United States
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Other studies related to the condition(s) this trial covers.
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