One-Minute chair test could revolutionize blood clot recovery prediction

NCT ID NCT06166329

Knowledge-focused Sponsor: University Hospital, Rouen Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a simple one-minute chair stand test can help doctors predict how well patients will recover from a non-severe pulmonary embolism (a blood clot in the lungs). Researchers will compare the test results with standard risk scores that use blood tests and heart imaging. If the chair test proves reliable, it could offer a quick, low-cost way to guide treatment decisions for hospitalized patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to: If successful, this simple test could become a standard tool to quickly assess recovery risk in pulmonary embolism patients without needing extra blood tests or scans.
What could go wrong: This is an early, single-center study with only 180 participants. The test may not prove accurate enough to replace current risk scores, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 180 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2024

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of pulmonary embolism according to clinical algorithm, confirmed by thoracic angioscan or ventilation perfusion (V/P) scan, * Non-serious pulmonary embolism, not requiring intensive care (thrombectomy or fibrinolysis not considered). * sPESI score ≥ 1 \[or = 0 with elevated troponin or presence of markers of VD dysfunction, or = 0 with need for hospitalization due to comorbidities unrelated to PE (social isolation, comprehension disorders, intercurrent infection, chronic renal failure, advanced cancer...) * Patients with no contraindications to chair lift testing (no O2 at the time of testing). * Effective anticoagulation for at least 1 hour. Exclusion Criteria: * sPESI score = 0 with outpatient referral. * Diagnostic confirmation of Pulmonia Embolism by thoracic angioscan or scintigraphy more than 24h after suspicion of diagnosis. * Hospitalization \> 24h after introduction of anticoagulation, with subsequent confirmation by scintigraphy. * Any sign of serious Pulmonia Embolism, requiring hospitalization in an intensive care unit. * Asymptomatic Pulmonia Embolism discovered by chance

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Conditions

The condition(s) this trial relates to.

pulmonary embolism Ventricular Dysfunction, Right

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Early prognostic evaluation Functional exercise testing Non-high-risk pulmonary embolism Non-severe pulmonary embolism Prognostic stratification Pulmonary embolism Pulmonary embolism acute Risk assessment in pulmonary embolism

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

1 site. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

Open the record ↗
A doctor treating you

A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

One-Minute chair test could revolutionize blood clot recovery prediction

What the study statuses mean