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New combo therapy aims to ease stubborn neck headaches without drugs

NCT ID NCT07373912

Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding instrument-assisted soft tissue mobilization (IASTM) to standard Mulligan therapy can better relieve cervicogenic headache—a headache that starts from the neck. Sixty adults with chronic neck-related headaches will receive the combined treatment. Researchers will measure changes in pain, neck movement, and disability to see if the combo works better than Mulligan therapy alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
instrument-assisted soft tissue mobilization (IASTM) and Mulligan therapy (SNAG technique)
What this could lead to
If it works, this could offer a better non-drug way to reduce pain and improve neck movement for people with cervicogenic headache.
What could go wrong
This is a small, early-stage trial with only 60 participants and no blinding, so results may not apply widely. The therapy is manual and depends on the therapist's skill.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Feb 2026

An estimate. Start dates often move.

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: -Unilateral CGH presentation * Age group above 18 years' old * History of chronic CGH (\>3 months) * CGH owing to cervical spine (neck) dysfunction * Reduced cervical motion * Neck stiffness and movement restriction Exclusion Criteria: * Participants with other types of headache (migraine headache) * Headache owing to other causes (sinus, tumor, neural, and tempero-mandibular joint issues) * Any contraindications to manual and manipulative therapy (fracture, instability, osteoporosis and neural symptoms) * Taking analgesics or corticosteroids and migraine-specific medications, such as triptans * Metastasis * Cardiac conditions (stroke and syncope) * Neurological conditions (radiculopathy, myelopathy)

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Conditions

The condition(s) this trial relates to.

Post-Traumatic Headache

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cervicogenic headache

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.