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Neck injection offers new hope for Tough-to-Treat PTSD

NCT ID NCT07382596

Symptom relief Sponsor: Dr. Dean Reeves Clinic Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 17, 2026 · Updated 2 times

Summary

This study tests whether a simple injection of dextrose (sugar water) into the neck can reduce symptoms like anxiety, brain fog, and depression in people with PTSD who haven't improved after trying multiple medications and therapies. About 50 adults will receive either the dextrose injection or a placebo (salt water) to see which works better. The goal is to find a new, low-risk option for those still struggling with PTSD.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Apr 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

19 to 90 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Inclusion Criteria: * Not involved in another study of PTSD treatment * Reliable transportation * Comfortable with computers * Tried 2 or more medications for treatment of PTSD symptoms * Tried 2 or more non-medication treatments for PTSD symptom * No known life-threatening illness * Not taking daily narcotics * Not having 3 or more alcoholic drinks on an average day * No active suicidal plans * No major surgery plans * No major life stress that might interfere with completing study * Symptoms for more than 1 year * Not planning to move for next 18 months. * Living within an hour of Portland, OR, Madison, WI, or Lexington, KY * Wiling to provide 2 email and 2 phone contact methods * Willing to answer questions on multiple occasions over the course of a year. * Willing to be assigned to 3 months of usual care treatment * No diagnosis of schizophrenia, Borderline Personality Disorder, or Bipolar Disorder. * No severe needle phobia * Chronic pain ≤ 5/10 * PCL-C score ≥ 50 Exclusion Criteria: \-

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Conditions

The condition(s) this trial relates to.

post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PTSD

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    4 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Medical Procedures of Wisconsin

    RECRUITING

    Madison, Wisconsin, 53709, United States

  • NW Regen

    RECRUITING

    Portland, Oregon, 97210, United States

  • Paul Johnson, MD.

    RECRUITING

    Portland, Oregon, 97210, United States

  • Wellward Medical

    RECRUITING

    Lexington, Kentucky, 40509, United States

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