Oxygen levels in cervical tumors may predict treatment success
NCT ID NCT01181375
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how low oxygen levels and fluid pressure inside cervical cancer tumors relate to how well radiation therapy works. Researchers will measure these factors in 500 patients before and during treatment. The goal is to find the best way to identify which patients might benefit from therapies that target the tumor environment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 500 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2006
- Expected to finish
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Aug 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Histologic diagnosis of cervix cancer 2. A decision to treat using radiation therapy according to the existing treatment policies of the PMH Gynecology Group 3. Clinical stage IB-IV with grossly evident cervical disease 4. No distant metastases 5. No cytotoxic anti-cancer therapy for cervical carcinoma prior to study entry 6. Signed informed consent Exclusion Criteria: \-
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Health Network, Princess Margaret Hospital
Toronto, Ontario, M5G 2M9, Canada
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Other studies related to the condition(s) this trial covers.
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