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New drug cocktail targets tough lung cancer

NCT ID NCT02393625

First seen Feb 03, 2026 · Last updated May 22, 2026 · Updated 13 times

Summary

This study tests the safety and effectiveness of combining two drugs, ceritinib and nivolumab, in adults with a specific type of advanced lung cancer called ALK-positive NSCLC. About 57 participants will receive the drug combination to find the best dose and see if tumors shrink. The goal is to control the disease, not cure it, as ongoing treatment is needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania, 19111, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Massachusetts General Hospital Thoracic Oncolgoy

    Boston, Massachusetts, 02115, United States

  • Mayo Clinic - Arizona

    Scottsdale, Arizona, 85259, United States

  • Novartis Investigative Site

    Heidelberg, Victoria, 3084, Australia

  • Novartis Investigative Site

    Leuven, Vlaams Brabant, 3000, Belgium

  • Novartis Investigative Site

    Toronto, Ontario, M5G 2M9, Canada

  • Novartis Investigative Site

    Hong Kong, 999077, Hong Kong

  • Novartis Investigative Site

    Milan, MI, 20133, Italy

  • Novartis Investigative Site

    Modena, MO, 41124, Italy

  • Novartis Investigative Site

    Singapore, 168583, Singapore

  • Novartis Investigative Site

    Barcelona, 08035, Spain

Conditions

Explore the condition pages connected to this study.