New drug combo shows promise for ALK-Positive lung cancer patients

NCT ID NCT02393625

First seen Feb 03, 2026 · Last updated May 08, 2026 · Updated 11 times

Summary

This early-stage study tests the safety and effectiveness of combining two drugs, ceritinib and nivolumab, in adults with a specific genetic type of advanced lung cancer called ALK-positive NSCLC. The goal is to find the best dose and see if the combination shrinks tumors. About 57 participants will receive the treatment, and researchers will monitor side effects and how long any benefits last.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania, 19111, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Massachusetts General Hospital Thoracic Oncolgoy

    Boston, Massachusetts, 02115, United States

  • Mayo Clinic - Arizona

    Scottsdale, Arizona, 85259, United States

  • Novartis Investigative Site

    Heidelberg, Victoria, 3084, Australia

  • Novartis Investigative Site

    Leuven, Vlaams Brabant, 3000, Belgium

  • Novartis Investigative Site

    Toronto, Ontario, M5G 2M9, Canada

  • Novartis Investigative Site

    Hong Kong, 999077, Hong Kong

  • Novartis Investigative Site

    Milan, MI, 20133, Italy

  • Novartis Investigative Site

    Modena, MO, 41124, Italy

  • Novartis Investigative Site

    Singapore, 168583, Singapore

  • Novartis Investigative Site

    Barcelona, 08035, Spain

Conditions

Explore the condition pages connected to this study.