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New standards could end the misery of mysterious 'Brain Tinnitus'

NCT ID NCT07560280

Knowledge-focused Sponsor: Beijing Shijitan Hospital, Capital Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to create clear guidelines for diagnosing and treating a condition called 'cerebral tinnitus syndrome,' where people hear sounds inside their head due to narrowed neck veins. Researchers will test a surgery to open the vein in 107 patients and track their symptoms for a year. The goal is to standardize care so patients stop bouncing between doctors without relief.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 369 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2025

Expected to finish

Dec 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age between 18 and 75 years, with no gender restriction. 2. Presence of one or more symptoms associated with "Cerebral Tinnitus Syndrome," with a duration of at least 3 months. 3. Following a detailed medical history and comprehensive physical examination, other known causes of cerebral tinnitus are preliminarily excluded, with suspected internal jugular vein stenosis (IJVS) as the cause. 4. Imaging studies (e.g., jugular ultrasound, cervical venous CT venography (CTV)) show significant stenosis in the internal jugular vein (stenosis degree ≥50%). 5. The patient has provided informed consent and voluntarily agrees to participate in the study, with a signed informed consent form. Exclusion Criteria: 1. Patients with a history of cranial surgery or diagnosed intracranial space-occupying lesions. 2. Patients with severe cardiac, hepatic, or renal insufficiency, or other systemic diseases. 3. Patients who have undergone any surgical or interventional procedures affecting jugular venous flow within the last 6 months. 4. Patients with a history of psychiatric disorders or cognitive impairment who cannot complete study evaluations. 5. Pregnant or breastfeeding women.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Assessment, self Diagnostic self evaluation Jugular vein anomaly (disorder) Nerosurgery

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Beijing Shijitan Hospital, Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, 100038, China

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