Brain blood flow in tiny patients: study seeks safe surgery limits
NCT ID NCT07660302
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study measures how well the brain controls its own blood flow in preterm and full-term infants during non-cardiac surgery. Using a special light-based monitor on the forehead, researchers track oxygen levels in the brain and compare them to blood pressure. The goal is to identify the blood pressure range that keeps the brain safe, which could guide anesthesia care for these vulnerable patients.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors set safer blood pressure targets for infants during surgery, potentially reducing brain injury risk.
- What could go wrong
- This is an observational study, not a treatment trial. It may not lead to immediate changes in care, and results may vary across individual infants.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 160 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Dec 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Preterm and term neonates and infants aged 0 days to 12 months undergoing non-cardiac surgery under general anesthesia for 60 minutes or longer at Seoul National University Children's Hospital.
- Ages
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0 days to 12 months
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Pediatric patients undergoing non-cardiac surgery under general anesthesia Expected duration of anesthesia of 60 minutes or longer Patients who meet one of the following age criteria: Preterm neonates: born at \<37 weeks of gestation and ≤1 month of postnatal age Preterm infants: born at \<37 weeks of gestation and 1-12 months of postnatal age Term neonates: born at ≥37 weeks of gestation and ≤1 month of postnatal age Term infants: born at ≥37 weeks of gestation and 1-12 months of postnatal age Written informed consent obtained from a parent or legal guardian Exclusion Criteria: * Presence of residual congenital heart disease * Undergoing cardiac surgery * Undergoing neurosurgery * Presence of severe brain malformation
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Seoul National University Hospital
Seoul, South Korea
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