Brain zapping study seeks clues to Autism's social challenges
NCT ID NCT05396352
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how a brain area called the cerebellum influences social and thinking abilities in young adults with and without autism. Researchers will use a gentle brain stimulation technique and brain scans to see how it changes these skills. The goal is to better understand the brain's role in autism, not to treat it directly. Participants must be 18-35, right-handed, native English speakers, and live near Washington, DC.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Jan 2022
- Expected to finish
-
Dec 2025
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 35 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Please note: This study takes place at American University and Georgetown University in Washington, DC. We do not have funds for travel and lodging available for this study, so participants should be local to the DC region. Inclusion Criteria: All participants * Aged 18-35 * Able to provide written, informed consent * NIH Toolbox age-adjusted Cognitive Function Composite standard score ≥ 85 * Native English speaker * Right-handed * Not pregnant * Able to attend all study sessions * Pass safety screening for MRI and neuromodulation (e.g. no metal in body, implanted devices, history of seizure, claustrophobia) Additional INCLUSION criteria for adults with autism Either * Prior research-reliable diagnosis of autism spectrum disorder (ASD) Or * Meet DSM-5 criteria for ASD confirmed with ADOS-2 via research-reliable clinical assessment Exclusion Criteria: Neurotypical adults * Age \<18 or \>35 * NIH Toolbox age-adjusted Cognitive Function Composite standard score \< 85 * Contraindications for MRI or neuromodulation with tDCS (e.g. metal in body, pacemaker or other implanted device, history of seizure, claustrophobia) * Current or prior history of neurological or neurodevelopmental condition or brain injury * Psychotropic medication * Pregnancy Adults with autism * Age \<18 or \>35 * Participants with a legal authorized representative * NIH Toolbox age-adjusted Cognitive Function Composite standard score \< 85 * Contraindications for MRI or neuromodulation with tDCS (e.g. metal in body, pacemaker or other implanted device, history of seizure, claustrophobia) * Pregnancy
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Autism are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
American University
RECRUITINGWashington D.C., District of Columbia, 20016, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can wireless monitors make ER vitals easier for autistic children?
- Why do some children with autism struggle with balance?
- Brain zaps tested to calm emotional storms in autism
- Can an AI chatbot help autism caregivers find their way?
- Pregnancy and birth clues: what raises autism risk?
- Can virtual reality boost thinking skills in kids with autism?