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New mammogram technique could spot hidden breast cancers

NCT ID NCT05667532

First seen Jan 09, 2026 · Last updated Jun 19, 2026 · Updated 26 times

Summary

This study is testing whether contrast-enhanced mammography (CEM) can find breast cancers better than standard mammography in women with dense breasts. Dense breast tissue can hide tumors on regular mammograms. The trial will enroll 1,000 women aged 30-75 with dense breasts to compare the two imaging methods. If CEM works well, it could become a new screening option for this high-risk group.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Contrast-Enhanced Mammography (CEM)

What this could lead to

If successful, CEM could become a more accurate screening tool for women with dense breasts, catching cancers earlier than standard mammography.

What could go wrong

This is an observational screening study, not a treatment trial. CEM may not prove significantly better, and results may not apply to all women or settings.

Conditions

The condition(s) this trial relates to.

breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.