New combo therapy aims to shrink tough rectal tumors before surgery
NCT ID NCT07580339
First seen May 13, 2026 · Last updated May 20, 2026 · Updated 2 times
Summary
This study tests whether adding an experimental drug (DCSZ11) to standard radiation and chemotherapy can improve outcomes for people with a high-risk type of rectal cancer. About 30 adults with mismatch repair proficient (pMMR) locally advanced rectal cancer will receive the combination before surgery. The main goal is to see if the cancer disappears or shrinks significantly, and to check for side effects.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Johns Hopkins SKCCC
Baltimore, Maryland, 21231, United States
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