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Engineered immune cells take aim at tough T-Cell cancers

NCT ID NCT03690011

First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 37 times

Summary

This early-phase trial tests a new cell therapy for people with hard-to-treat T-cell leukemia or lymphoma. Researchers take a patient's own immune T-cells, modify them in the lab to recognize and attack cancer cells carrying the CD7 protein, and infuse them back. The main goals are to check safety and see if the treatment can shrink tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

Conditions

The condition(s) this trial relates to.

non-Hodgkin lymphoma Precursor T-Cell Lymphoblastic Leukemia-Lymphoma T-cell acute lymphoblastic leukemia T-lymphoblastic lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.