Engineered immune cells take aim at tough T-Cell cancers

NCT ID NCT03690011

Recruiting now Disease control Sponsor: Baylor College of Medicine Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 24 times

Summary

This early-phase trial tests a new cell therapy for people with hard-to-treat T-cell leukemias or lymphomas. Doctors take a patient's own T cells, add a special receptor (CD7.CAR) to help them recognize and attack cancer cells, and then return them to the patient. The main goal is to check safety and find the right dose, while also seeing if the treatment can shrink tumors. About 27 participants will be enrolled.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Houston Methodist Hospital
RECRUITING

Houston, Texas, 77030, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Texas Children's Hospital
RECRUITING

Houston, Texas, 77030, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA T-CELL ACUTE LYMPHOBLASTIC LYMPHOMA T-CELL ACUTE LYMPHOBLASTIC LYMPHOMA T-NON-HODGKIN LYMPHOMA T-NON-HODGKIN LYMPHOMA