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Engineered T-Cells take aim at Hard-to-Treat blood cancers

NCT ID NCT03829540

First seen Nov 06, 2025 · Last updated Apr 30, 2026 · Updated 22 times

Summary

This early-phase study tests a new treatment called CD4CAR for people with T-cell leukemia or lymphoma that has come back or not responded to standard therapy. The treatment uses a patient's own immune cells, modified in a lab to target and attack cancer cells. The main goal is to see if the therapy is safe and feasible in about 20 participants aged 12 and older.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Albert Einstein Health Network

    RECRUITING

    New York, New York, 10467, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Indiana University Melvin and Bren Simon Comprehensive Cancer Center

    RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Riley Hospital for Children

    RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Stony Brook Cancer Center

    ACTIVE_NOT_RECRUITING

    Stony Brook, New York, 11794, United States

  • The University of Texas MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Miami Sylvester Comprehensive Cancer Center

    RECRUITING

    Miami, Florida, 33136, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.