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Supercharged immune cells take on advanced melanoma in new trial

NCT ID NCT06961357

First seen Nov 12, 2025 · Last updated May 23, 2026 · Updated 24 times

Summary

This study tests a new way to treat advanced melanoma by boosting a patient's own immune cells (TIL) with a molecule called CD40L. After removing a tumor, the cells are grown in a lab, strengthened, and given back to the patient along with chemotherapy and short-term IL-2. The goal is to see if this approach can shrink tumors and control the disease in people who have not responded to standard treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact

Conditions

Explore the condition pages connected to this study.