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Immune-Boosting cocktail aims to shrink Head/Neck tumors before surgery

NCT ID NCT06159621

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 24 times

Summary

This early-phase study tests two experimental drugs (LVGN7409 and LVGN3616) given together before surgery for people with HPV-negative head and neck cancer. The goal is to see if this combination is safe and can activate the immune system to attack the tumor. About 27 adults will take part, and researchers will compare immune cell levels in tumor samples taken before and after treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.