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Engineered immune cells take aim at childhood leukemias in early trial

NCT ID NCT04318678

First seen Nov 01, 2025 · Last updated May 21, 2026 · Updated 29 times

Summary

This early-phase trial tests a new treatment called CD123-CAR T-cell therapy for children and young adults (up to age 21) with certain blood cancers that have come back or not responded to standard treatment. The therapy uses the patient's own or a donor's immune cells, which are modified to recognize and attack cancer cells. The main goal is to find the safest dose and understand side effects, while also checking if the treatment can reduce or eliminate the cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • St Jude Children's Research Hospital

    RECRUITING

    Memphis, Tennessee, 38105, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • St. Jude Children's Research Hospital

    RECRUITING

    Memphis, Tennessee, 38105, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.