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Leukemia study checks if current treatments still work well

NCT ID NCT05070208

Knowledge-focused Sponsor: Acute Leukemia French Association Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked back at the medical records of 400 adults with a specific type of acute myeloid leukemia called core binding factor (CBF) leukemia. Researchers wanted to see how well current treatments work and what factors affect outcomes, such as genetic mutations and signs of leftover disease. The goal is to improve future treatment plans.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

400 people

The number who actually took part.

Started

Sep 2021

Finished

May 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Core Binding Factor Acute Myeloid Leukemia

Ages

18 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients over 18 years old * Diagnosis of acute myeloid leukemia with CBF confirmed by cytogenetics (karyotype and / or FISH): t (8; 21), inv (16) or t (16; 16) and / or molecular biology (RUNX1-RUNX1T1 fusions or CBFB-MYH11) * Initial management by intensive chemotherapy, hypomethylants or targeted therapies Exclusion Criteria: \- Opposition expressed to research

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Conditions

The condition(s) this trial relates to.

core binding factor acute myeloid leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute myeloblastic leukemia core binding factor

Contacts and locations

Locations

  • AP-HP-GHU - Hôpital AVICENNE

    Bobigny, France

  • CH Métropole Savoie

    Chambéry, France

  • CHU

    Lille, 59037, France

  • CHU La Conception

    Marseille, France

  • CHU Nice,Hopital Archet 1

    Nice, France

  • CHU de la cote de Nacre

    Caen, France

  • Centre Antoine Lacassagne

    Nice, France

  • Centre Hospitalier Lyon Sud

    Pierre-Bénite, France

  • Centre Hospitalier René Dubos

    Pontoise, France

  • Centre Hospitalier Victor Dupouy

    Argenteuil, France

  • Centre Hospitalier de Dunkerque

    Dunkirk, France

  • Centre Hospitalier de Roubaix

    Roubaix, France

  • Centre Hospitalier de St Quentin

    Saint-Quentin, France

  • Centre Hospitalier de Versailles André Mignot

    Le Chesnay, France

  • Centre hospitalier Sud Francilien

    Corbeil-Essonnes, France

  • Chu Amiens

    Amiens, France

  • Dijon Chu

    Dijon, France

  • Henri Mondor Aphp

    Créteil, France

  • Hopital Pitié-Salpétrière APHP

    Paris, France

  • Hôpital MILITAIRE PERCY

    Clamart, France

  • Hôpital Necker - APHP

    Paris, France

  • Hôpital Saint Louis- APHP

    Paris, France

  • Institut Gustave Roussy

    Villejuif, France

  • LENS CHR

    Lens, France

  • Limoges Chu

    Limoges, France

  • Saint Antoine

    Paris, France