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Cataract surgery comfort: higher eye pressure may reduce pain

NCT ID NCT07223866

Symptom relief Sponsor: Matthew Rauen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether keeping eye pressure more natural during cataract surgery helps patients feel less pain and need fewer pain medicines. About 85 people having cataract surgery in both eyes will take part. The goal is to see if a higher, more normal pressure makes the surgery more comfortable.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 85 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Nov 2025

An estimate. Start dates often move.

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Subjects who will require bilateral cataract surgery will be considered. Evaluations will occur in the clinic of the Principal Investigator (PI) Matthew Rauen, MD at the Wolfe Eye Clinic. Inclusion Criteria: * Visually significant cataract 2-3+ undergoing uncomplicated cataract surgery with similar cataract grade in both eyes * Unremarkable ocular health but inclusive of early AMD Exclusion Criteria: * H/o ocular surgery including corneal refractive surgery * Compromised zonular integrity or stability * Uncontrolled diabetes and diabetic retinopathy * Small pupils * H/o systemic inflammatory disease/uveitis * H/o chronic pain medications (including narcotics) and benzodiazepine usage * Abnormal liver or renal function

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Conditions

The condition(s) this trial relates to.

cataract nuclear cataract

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cataract and iol surgery Cataract surgery anesthesia Cataract surgery experience Nuclear cataract

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Wolfe Eye Clinic and Wolfe Surgery Center

    West Des Moines, Iowa, 50266, United States

More trials for these conditions

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