Cortisone or saline? new study aims to find best shot for wrist pain
NCT ID NCT06882603
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two common injection treatments—cortisone and saline—for carpal tunnel syndrome, a condition causing wrist pain and numbness. About 90 adults aged 18-65 with confirmed carpal tunnel will receive one of the injections plus exercise therapy. Researchers will measure nerve function, pain, and wrist ultrasound findings before and 12 weeks after treatment to see which approach works better.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 90 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Oct 2025
- Expected to finish
-
May 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 65 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Female and male patients aged 18-65 who applied to Ahi Evran University Physical Medicine and Rehabilitation Polyclinic and diagnosed with carpal tunnel syndrome through clinical and EMG 2. Patients who can understand the information form correctly and are cooperative 3. Patients who consented to participate in the study according to the informed consent form Exclusion Criteria: 1. Cervical radiculopathy 2. Polyneuropathy 3. Brachial plexopathy 4. Systemic corticosteroid use 5. History of fracture and trauma in the forearm and wrist on the treated side 6- Inflammatory rheumatic disease 7- Pregnant and breastfeeding patients 8- Systemic diseases such as renal failure, peptic ulcer, diabetes, hypothyroidism, coagulation disorders 9- Patients who have undergone carpal tunnel syndrome surgery 10- Thoracic outlet syndrome 11- Thenar atrophy, severe carpal tunnel syndrome 12- Patient is unwilling or states that they cannot participate for any reason
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Carpal tunnel syndrome (CTS) are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
2 sites. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Ahi Evran University
RECRUITINGKırşehir, City Centre, 40100, Turkey (Türkiye)
-
Ahi Evran University
RECRUITINGKırşehir, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Three shots, one wrist: which injection best eases carpal tunnel?
- Scalpel vs sound waves: two carpal tunnel surgeries go head to head
- Can carpal tunnel surgery restore more than hand function?
- Does nerve healing keep pace with hand recovery after carpal tunnel surgery?
- Retraining the brain to ease carpal tunnel pain: a new approach put to the test
- Can a Two-Session acupuncture treatment match ten sessions for carpal tunnel?