New needle combo may ease carpal tunnel pain without surgery
NCT ID NCT07324005
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests if combining two needle-based treatments works better than either alone for carpal tunnel syndrome. The treatments are a needle release of a wrist ligament and a dextrose (sugar water) injection around the nerve. The study will include 102 adults with moderate to severe symptoms lasting at least 3 months. Participants will be followed for up to 6 months to measure pain, function, and nerve size.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 102 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Dec 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * age between 20 to 80 years old * diagnosed with CTS on the basis of clinical condition and an electrophysiological analysis * the NRS of pain or paresthesia≧3 * with symptoms lasting for a minimum of 3 months. Exclusion Criteria: * history of polyneuropathy, thoracic outlet syndrome, brachial plexopathy, or inflammatory arthropathy * onset of CTS during pregnancy, hypothyroidism, or systemic infection * previous corticosteroid injection or wrist surgery for CTS * hypersensitivity to dextrose injection * the anatomic structure of the wrist is not suitable for needle release of TCL.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Shin Kong Wu Ho-Su Memorial Hospital
RECRUITINGTaipei, Taiwan
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