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Sugar water injection may ease carpal tunnel pain

NCT ID NCT07524933

Symptom relief Sponsor: Antalya Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether injecting a 5% dextrose (sugar water) solution around the nerve in the wrist can reduce pain and improve hand function in people with mild to moderate carpal tunnel syndrome. About 96 adults who haven't gotten better with standard care will receive the injection under ultrasound guidance. Researchers will measure pain, hand function, nerve size, and electrical activity to see if this simple treatment works.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
5% dextrose (sugar water) injection
What this could lead to
If it works, this could offer a non-surgical option to reduce pain and improve hand function for people with carpal tunnel syndrome.
What could go wrong
This is a small, early-stage trial with no phase, so results may not be conclusive. The injection is compared to a placebo, so any benefit might be due to the procedure itself rather than the sugar water.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

96 people

The number who actually took part.

Started

Jan 2026

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18-80 years * Clinical and electrophysiological diagnosis of mild to moderate carpal tunnel syndrome * Symptom duration of at least 3 months * Both male and female participants * Patients who have not responded adequately to conservative treatment * Patients who do not wish to undergo surgical treatment * Ability to provide informed consent Exclusion Criteria: * Severe or very severe carpal tunnel syndrome based on EMG findings * Previous injection therapy for carpal tunnel syndrome * Prior wrist or carpal tunnel surgery * Polyneuropathy or other peripheral neuropathies * Cervical radiculopathy or proximal median nerve entrapment * Brachial plexopathy or thoracic outlet syndrome * Pregnancy * Malignancy * Local or systemic infection * Cognitive impairment affecting cooperation * Systemic diseases affecting the median nerve (e.g., uncontrolled diabetes mellitus, thyroid disorders)

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Conditions

The condition(s) this trial relates to.

carpal tunnel syndrome disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Conditions

Contacts and locations

Locations

  • Antalya Eğitim Araştırma Hastanesi

    Antalya, Turkey (Türkiye)

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