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Artery test may unlock secrets of dementia types

NCT ID NCT07205003

Knowledge-focused Sponsor: University Hospital, Rouen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether the 'stickiness' or viscosity of the carotid artery wall differs between people with vascular dementia and those with Alzheimer's disease. Researchers will measure artery wall viscosity in 140 older adults using ultrasound and pressure sensors. The goal is to find a new way to tell these two common dementia types apart, which could lead to better diagnosis and care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better distinguish between vascular dementia and Alzheimer's disease using a simple artery test.
What could go wrong
This is an early observational study with only 140 participants, so results may not apply to everyone. It measures a new marker, not a treatment, so direct patient benefits are uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 140 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2022

Expected to finish

May 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

140 sujets dont 55 sujets avec démence vasculaire et 55 avec une démence de type maladie d'Alzheimer et 30 avec plainte mnésique sans troubles neurocognitifs.

Ages

70 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age over 70 * Memory consultation consultant (neurology or geriatrics) * Brain MRI less than one year old or planned as part of the cognitive assessment performed. * Patient diagnosed with Alzheimer's disease according to DSM-5 criteria or vascular dementia according to DSM-5 criteria, or presenting a memory complaint without evidence of a dementia-related condition. * No objection from the patient or their caregiver. * Patient covered by a health insurance plan Exclusion Criteria: * Known unilateral or bilateral carotid stenosis or history of carotid surgery * Permanent CA/AF * Patient presenting with confusion * Known psychiatric illness (severe depression, psychosis, etc.) * Non-vascular, non-Alzheimer's dementia (e.g., Lewy Body Dementia, Parkinsonian Dementia, Progressive Supranuclear Palsy) * Refusal to participate * MMS less than or equal to 10 * Contraindication to performing an MRI * Any acute decompensated pathology * Patient under guardianship or curatorship

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Conditions

The condition(s) this trial relates to.

Alzheimer disease cognitive disorder vascular dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alzheimer'S disease Neurocognitive disorders

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University Rouen Hospital

    RECRUITING

    Rouen, 76031, France

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