Phone therapy aims to lift spirits of elderly cancer patients
NCT ID NCT04452825
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new phone-based therapy called CARE (Cancer and Aging: Reflections for Elders) to help older adults with cancer who feel depressed or distressed. About 459 participants aged 70 and older will receive either CARE or standard supportive counseling over the phone. Researchers will compare which approach better reduces anxiety and depression.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Cancer and Aging: Reflections for Elders (CARE) psychotherapy
- What this could lead to
- If it works, this could provide a simple, phone-based therapy to improve mental health in older cancer patients.
- What could go wrong
- This is a behavioral intervention study, so results depend on patient engagement and may not apply to all. It is not a cure or disease treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 459 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2021
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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70 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * As per self-report or medical record, ≥ 70 years of age * As per self-report or medical record, has a diagnosis of cancer * As per self-report or medical record, receiving active treatment (e.g., radiation, chemotherapy, hormone); OR received active treatment in the past 6 months (N/A for training case participants); OR are currently on active surveillance with follow-ups at least approximately every 6 months * Received a HADS-D score of ≥ 6 or HADS-A score of ≥ 6 or a score of ≥ 4 on the distress thermometer. (N/A for training case participants) * Received a Karnofsky Performance Rating Scale (KPRS) score of ≥ 60 (N/A for training case participants) * Received a Blessed Orientation-Memory-Concentration Scale (BOMC) score of ≤ 11 (N/A for training case participants) * Fluent in English, as per self-reported fluency of "well" or "very well"\* Exclusion Criteria: * As per self-report, currently taking antidepressant medication for \< 3 months * As per self-report, currently receiving hospice care * In the judgment of the consenting professional is unable to provide informed consent and complete study sessions and assessment * As per self-report or as documented in the medical record, current untreated (e.g., no medication, no therapy) major psychotic disorder (schizotypal personality disorder, schizophreniform disorder, schizoaffective disorder). Patients diagnosed with a major psychiatric disorder will be reviewed by the study PI to determine eligibility prior to consent. * Language verification: Prior to enrollment, patients will be asked the following two questions by research staff to verify English fluency necessary for participation in the study: 1. How well do you speak English? (must respond "Well" or "Very well" when given the choices of Very well, Well, Not well, Not at all, Don't know, or Refused) 2. What is your preferred language for healthcare? (must respond English)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
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