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Heart CT study aims to sharpen risk prediction for coronary artery disease

NCT ID NCT04936867

Knowledge-focused Sponsor: Johann Wolfgang Goethe University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study enrolled 100 adults who were already scheduled for a cardiac CT scan for clinical reasons. Researchers wanted to see how well the scans could help diagnose coronary artery disease and predict future heart problems. They also looked at the balance between benefits and risks, such as radiation exposure and follow-up procedures. The goal is to improve how doctors use cardiac CT scans to assess heart disease risk.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better understand who might benefit most from cardiac CT scans and improve risk prediction for heart disease.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly change patient care. Results may not apply to all populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

100 people

The number who actually took part.

Started

Jul 2017

Finished

Jan 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adults referred to clinical cardiac computertomography imaging

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adults (=/\>18 years of age) 2. Able to provide informed consent 3. Clinical indication for cardio-CT in line with the latest clinical guidelines Exclusion Criteria: 1. standard contraindications to CT (in line with local roles and guidelines - please see Appendix) 2. known allergy to iodinated contrast agent 3. suspected acute kidney injury 4. unstable hemodynamic status or arrhythmias 5. suspected acute coronary syndrome 6. manifest thyrotoxicosis

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Coronary artery disease (CAD)

Contacts and locations

Locations

  • Institute for experimental and translational cardiovascular imaging

    Frankfurt am Main, Hesse, 60596, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.