Scientists test new method to Fine-Tune cancer drug doses

NCT ID NCT03997370

Ongoing Knowledge-focused Sponsor: NRG Oncology Source: ClinicalTrials.gov ↗

Summary

This study aims to find a better way to calculate the right dose of the chemotherapy drug carboplatin for cancer patients. Researchers are testing if a special dye (iohexol) can help doctors measure kidney function more accurately than standard blood tests, which is key for safe carboplatin dosing. The study involves 318 adult male patients who are already scheduled to receive carboplatin as part of their cancer treatment. The goal is to gather knowledge that could make future chemotherapy dosing more precise and potentially safer.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Armes Family Cancer Center

Findlay, Ohio, 45840, United States
Arnot Ogden Medical Center/Falck Cancer Center

Elmira, New York, 14905, United States
Asplundh Cancer Pavilion

Willow Grove, Pennsylvania, 19090, United States
Atrium Medical Center-Middletown Regional Hospital

Franklin, Ohio, 45005-1066, United States
Banner University Medical Center - Tucson

Tucson, Arizona, 85719, United States
Baystate Medical Center

Springfield, Massachusetts, 01199, United States
Benefis Helena Specialty Center

Helena, Montana, 59601, United States
Benefis Sletten Cancer Institute

Great Falls, Montana, 59405, United States
Billings Clinic Cancer Center

Billings, Montana, 59101, United States
Billings Clinic-Cody

Cody, Wyoming, 82414, United States
Blanchard Valley Hospital

Findlay, Ohio, 45840, United States
Bozeman Health Deaconess Hospital

Bozeman, Montana, 59715, United States
Broadlawns Medical Center

Des Moines, Iowa, 50314, United States
CARTI Cancer Center

Little Rock, Arkansas, 72205, United States
Cancer Care and Hematology-Fort Collins

Fort Collins, Colorado, 80528, United States
Cancer Center-Metro Medical Center Bayamon

Bayamón, 00959-5060, Puerto Rico
Carle BroMenn Medical Center

Normal, Illinois, 61761, United States
Carle Cancer Center

Urbana, Illinois, 61801, United States
Carle Cancer Institute Normal

Normal, Illinois, 61761, United States
Carle Physician Group-Effingham

Effingham, Illinois, 62401, United States
Carle Physician Group-Mattoon/Charleston

Mattoon, Illinois, 61938, United States
Carle at The Riverfront

Danville, Illinois, 61832, United States
Central Care Cancer Center - Bolivar

Bolivar, Missouri, 65613, United States
Central Care Cancer Center - Garden City

Garden City, Kansas, 67846, United States
Central Care Cancer Center - Great Bend

Great Bend, Kansas, 67530, United States
Centro Comprensivo de Cancer de UPR

San Juan, 00927, Puerto Rico
Clara Maass Medical Center

Belleville, New Jersey, 07109, United States
Cleveland Clinic Cancer Center/Fairview Hospital

Cleveland, Ohio, 44111, United States
Cleveland Clinic Foundation

Cleveland, Ohio, 44195, United States
Community Hospital of Anaconda

Anaconda, Montana, 59711, United States
Community Medical Center

Missoula, Montana, 59804, United States
Community Medical Center

Toms River, New Jersey, 08755, United States
Cox Cancer Center Branson

Branson, Missouri, 65616, United States
CoxHealth South Hospital

Springfield, Missouri, 65807, United States
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center

Lebanon, New Hampshire, 03756, United States
Dayton Physician LLC - Englewood

Dayton, Ohio, 45415, United States
Dayton Physicians LLC - Troy

Troy, Ohio, 45373, United States
Dayton Physicians LLC-Atrium

Franklin, Ohio, 45005, United States
Dayton Physicians LLC-Miami Valley South

Centerville, Ohio, 45459, United States
Dayton Physicians LLC-Wayne

Greenville, Ohio, 45331, United States
Doctors Cancer Center

Manatí, 00674, Puerto Rico
Emory University Hospital Midtown

Atlanta, Georgia, 30308, United States
Emory University Hospital/Winship Cancer Institute

Atlanta, Georgia, 30322, United States
First Dayton Cancer Care

Kettering, Ohio, 45420, United States
Freeman Health System

Joplin, Missouri, 64804, United States
Good Samaritan University Hospital

West Islip, New York, 11795, United States
Great Falls Clinic

Great Falls, Montana, 59405, United States
Greater Dayton Cancer Center

Kettering, Ohio, 45409, United States
HIMA San Pablo Oncologic Hospital

Caguas, 00726, Puerto Rico
Hartford Hospital

Hartford, Connecticut, 06102, United States
Heartland Regional Medical Center

Saint Joseph, Missouri, 64506, United States
Hematology/Oncology Clinic PLLC

Baton Rouge, Louisiana, 70809, United States
Hi-Line Sletten Cancer Center

Havre, Montana, 59501, United States
Highland Hospital

Rochester, New York, 14620, United States
Hillcrest Hospital Cancer Center

Mayfield Heights, Ohio, 44124, United States
Huntsman Cancer Institute/University of Utah

Salt Lake City, Utah, 84112, United States
Idaho Urologic Institute-Meridian

Meridian, Idaho, 83642, United States
Indu and Raj Soin Medical Center

Beavercreek, Ohio, 45431, United States
Instituto Oncologia Moderna Ponce

Ponce, 00716, Puerto Rico
Iowa Lutheran Hospital

Des Moines, Iowa, 50316, United States
Iowa Methodist Medical Center

Des Moines, Iowa, 50309, United States
Jefferson Cherry Hill Hospital

Cherry Hill, New Jersey, 08002, United States
Johns Hopkins University/Sidney Kimmel Cancer Center

Baltimore, Maryland, 21287, United States
Kettering Medical Center

Kettering, Ohio, 45429, United States
Kootenai Clinic Cancer Services - Post Falls

Post Falls, Idaho, 83854, United States
Kootenai Clinic Cancer Services - Sandpoint

Sandpoint, Idaho, 83864, United States
Kootenai Health - Coeur d'Alene

Coeur d'Alene, Idaho, 83814, United States
Lake Regional Hospital

Osage Beach, Missouri, 65065, United States
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

Savannah, Georgia, 31405, United States
Logan Health Medical Center

Kalispell, Montana, 59901, United States
Medical Center of the Rockies

Loveland, Colorado, 80538, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Memorial Hospital of Laramie County

Cheyenne, Wyoming, 82001, United States
Memorial Sloan Kettering Basking Ridge

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Bergen

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Memorial Sloan Kettering Commack

Commack, New York, 11725, United States
Memorial Sloan Kettering Monmouth

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau

Uniondale, New York, 11553, United States
Memorial Sloan Kettering Westchester

Harrison, New York, 10604, United States
Mercy Cancer Center - Cape Girardeau

Cape Girardeau, Missouri, 63703, United States
Mercy Clinic-Rolla-Cancer and Hematology

Rolla, Missouri, 65401, United States
Mercy Hospital Fort Smith

Fort Smith, Arkansas, 72903, United States
Mercy Hospital Joplin

Joplin, Missouri, 64804, United States
Mercy Hospital Oklahoma City

Oklahoma City, Oklahoma, 73120, United States
Mercy Hospital Pittsburg

Pittsburg, Kansas, 66762, United States
Mercy Hospital Saint Louis

St Louis, Missouri, 63141, United States
Mercy Hospital South

St Louis, Missouri, 63128, United States
Mercy Hospital Springfield

Springfield, Missouri, 65804, United States
Mercy Hospital Washington

Washington, Missouri, 63090, United States
Mercy Infusion Center - Chippewa

St Louis, Missouri, 63109, United States
Mercy Oncology and Hematology - Clayton-Clarkson

Ballwin, Missouri, 63011, United States
Methodist West Hospital

West Des Moines, Iowa, 50266-7700, United States
Miami Valley Cancer Care and Infusion

Greenville, Ohio, 45331, United States
Miami Valley Hospital

Dayton, Ohio, 45409, United States
Miami Valley Hospital North

Dayton, Ohio, 45415, United States
Miami Valley Hospital South

Centerville, Ohio, 45459, United States
Monmouth Medical Center

Long Branch, New Jersey, 07740, United States
Monongalia Hospital

Morgantown, West Virginia, 26505, United States
Montefiore Medical Center - Moses Campus

The Bronx, New York, 10467, United States
Montefiore Medical Center-Einstein Campus

The Bronx, New York, 10461, United States
Montefiore Medical Center-Weiler Hospital

The Bronx, New York, 10461, United States
Newark Beth Israel Medical Center

Newark, New Jersey, 07112, United States
NorthShore University HealthSystem-Evanston Hospital

Evanston, Illinois, 60201, United States
NorthShore University HealthSystem-Glenbrook Hospital

Glenview, Illinois, 60026, United States
NorthShore University HealthSystem-Highland Park Hospital

Highland Park, Illinois, 60035, United States
Northwestern Medicine Lake Forest Hospital

Lake Forest, Illinois, 60045, United States
Northwestern University

Chicago, Illinois, 60611, United States
OSF Saint Anthony's Health Center

Alton, Illinois, 62002, United States
Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
Oncology Hematology Care Inc-Kenwood

Cincinnati, Ohio, 45236, United States
Orion Cancer Care

Findlay, Ohio, 45840, United States
PROncology

San Juan, 00927, Puerto Rico
Phelps Health Delbert Day Cancer Institute

Rolla, Missouri, 65401, United States
Poudre Valley Hospital

Fort Collins, Colorado, 80524, United States
Primary Care Physician Group

San Juan, 00920, Puerto Rico
Puerto Rico Hematology Oncology Group

Bayamón, 00961, Puerto Rico
Reid Health

Richmond, Indiana, 47374, United States
Robert Wood Johnson University Hospital Somerset

Somerville, New Jersey, 08876, United States
Roswell Park Cancer Institute

Buffalo, New York, 14263, United States
Rutgers Cancer Institute of New Jersey

New Brunswick, New Jersey, 08903, United States
Rutgers New Jersey Medical School

Newark, New Jersey, 07101, United States
SSM Health Good Samaritan

Mount Vernon, Illinois, 62864, United States
Saint Alphonsus Cancer Care Center-Baker City

Baker City, Oregon, 97814, United States
Saint Alphonsus Cancer Care Center-Boise

Boise, Idaho, 83706, United States
Saint Alphonsus Cancer Care Center-Caldwell

Caldwell, Idaho, 83605, United States
Saint Alphonsus Cancer Care Center-Nampa

Nampa, Idaho, 83687, United States
Saint Alphonsus Cancer Care Center-Ontario

Ontario, Oregon, 97914, United States
Saint Anthony Regional Hospital

Carroll, Iowa, 51401, United States
Saint Barnabas Medical Center

Livingston, New Jersey, 07039, United States
Saint Elizabeth Boardman Hospital

Boardman, Ohio, 44512, United States
Saint Elizabeth Healthcare Edgewood

Edgewood, Kentucky, 41017, United States
Saint Elizabeth Youngstown Hospital

Youngstown, Ohio, 44501, United States
Saint Joseph Warren Hospital

Warren, Ohio, 44484, United States
Saint Joseph's/Candler - Bluffton Campus

Bluffton, South Carolina, 29910, United States
Saint Mary's Hospital

Centralia, Illinois, 62801, United States
San Juan City Hospital

San Juan, 00936, Puerto Rico
San Juan Community Oncology Group

San Juan, 00917, Puerto Rico
Sibley Memorial Hospital

Washington D.C., District of Columbia, 20016, United States
Sidney Kimmel Cancer Center Washington Township

Sewell, New Jersey, 08080, United States
Springfield Regional Cancer Center

Springfield, Ohio, 45504, United States
Springfield Regional Medical Center

Springfield, Ohio, 45504, United States
State University of New York Upstate Medical University

Syracuse, New York, 13210, United States
The Cancer Institute at Saint Francis Hospital

East Hills, New York, 11548, United States
The Carle Foundation Hospital

Urbana, Illinois, 61801, United States
The Hospital of Central Connecticut

New Britain, Connecticut, 06050, United States
Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, 19107, United States
Trinitas Hospital and Comprehensive Cancer Center - Williamson Street Campus

Elizabeth, New Jersey, 07207, United States
Tulane University School of Medicine

New Orleans, Louisiana, 70112, United States
UC Comprehensive Cancer Center at Silver Cross

New Lenox, Illinois, 60451, United States
UC San Diego Health System - Encinitas

Encinitas, California, 92024, United States
UC San Diego Medical Center - Hillcrest

San Diego, California, 92103, United States
UC San Diego Moores Cancer Center

La Jolla, California, 92093, United States
UCHealth Greeley Hospital

Greeley, Colorado, 80631, United States
UCHealth University of Colorado Hospital

Aurora, Colorado, 80045, United States
UI Health Care Mission Cancer and Blood - Ankeny Clinic

Ankeny, Iowa, 50023, United States
UI Health Care Mission Cancer and Blood - Des Moines Clinic

Des Moines, Iowa, 50309, United States
UI Health Care Mission Cancer and Blood - Laurel Clinic

Des Moines, Iowa, 50314, United States
UI Health Care Mission Cancer and Blood - Waukee Clinic

Waukee, Iowa, 50263, United States
UI Health Care Mission Cancer and Blood - West Des Moines Clinic

Clive, Iowa, 50325, United States
UI Healthcare Mission Cancer and Blood - Fort Dodge

Fort Dodge, Iowa, 50501, United States
University of Arizona Cancer Center-North Campus

Tucson, Arizona, 85719, United States
University of Arizona Cancer Center-Orange Grove Campus

Tucson, Arizona, 85704, United States
University of Arkansas for Medical Sciences

Little Rock, Arkansas, 72205, United States
University of California Davis Comprehensive Cancer Center

Sacramento, California, 95817, United States
University of Chicago Comprehensive Cancer Center

Chicago, Illinois, 60637, United States
University of Chicago Medicine-Orland Park

Orland Park, Illinois, 60462, United States
University of Cincinnati Cancer Center-UC Medical Center

Cincinnati, Ohio, 45219, United States
University of Cincinnati Cancer Center-West Chester

West Chester, Ohio, 45069, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
University of Pittsburgh Cancer Institute (UPCI)

Pittsburgh, Pennsylvania, 15232, United States
University of Rochester

Rochester, New York, 14642, United States
University of Utah Sugarhouse Health Center

Salt Lake City, Utah, 84106, United States
Upper Valley Medical Center

Troy, Ohio, 45373, United States
VCU Massey Cancer Center at Stony Point

Richmond, Virginia, 23235, United States
VCU Massey Comprehensive Cancer Center

Richmond, Virginia, 23298, United States
Vanderbilt Breast Center at One Hundred Oaks

Nashville, Tennessee, 37204, United States
Vanderbilt University/Ingram Cancer Center

Nashville, Tennessee, 37232, United States
Vanderbilt-Ingram Cancer Center Cool Springs

Franklin, Tennessee, 37067, United States
Vanderbilt-Ingram Cancer Center at Franklin

Franklin, Tennessee, 37067, United States
Walter Knox Memorial Hospital

Emmett, Idaho, 83617, United States
Walter Reed National Military Medical Center

Bethesda, Maryland, 20889-5600, United States
Wayne Hospital

Greenville, Ohio, 45331, United States
Wayne State University/Karmanos Cancer Institute

Detroit, Michigan, 48201, United States
Weisberg Cancer Treatment Center

Farmington Hills, Michigan, 48334, United States
Welch Cancer Center

Sheridan, Wyoming, 82801, United States
West Penn Hospital

Pittsburgh, Pennsylvania, 15224, United States
Women and Infants Hospital

Providence, Rhode Island, 02905, United States
Women's Cancer Center of Nevada

Las Vegas, Nevada, 89106, United States

Conditions

Explore the condition pages connected to this study.

MALIGNANT SOLID NEOPLASM