Scientists test 'Living Drug' to reset immune system in devastating autoimmune diseases
NCT ID NCT06544330
Summary
This is an early-stage safety study testing a new two-part cell therapy for people with severe autoimmune diseases like lupus and scleroderma that haven't responded to other treatments. Doctors will collect a patient's own immune cells, genetically modify them to target a specific protein (CD19), and infuse them back, followed by a supporting drug (STK-009). The main goal is to see if this combination is safe and tolerable, while also checking if it helps control the disease.
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Contacts and locations
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Locations
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Feinstein Institutes for Medical Research
Manhasset, New York, 11030, United States
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Hackensack University Medical Center
Hackensack, New Jersey, 07601, United States
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HonorHealth Research Institute
Scottsdale, Arizona, 85258, United States
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Ohio State University Wexner Medical Center
Columbus, Ohio, 43210, United States
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The Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States
Conditions
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