Could CAR-T therapy tame severe vasculitis? new trial launches
NCT ID NCT06868290
First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 19 times
Summary
This study tests a new treatment called rapcabtagene autoleucel (a CAR-T cell therapy) against standard care for people with severe active vasculitis (GPA or MPA). About 126 adults aged 18–75 with confirmed ANCA antibodies and active disease will be enrolled. The goal is to see if this one-time cell therapy can better control the disease and reduce the need for long-term steroids.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ANCA-ASSOCIATED VASCULITIS (AAV) are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Baylor University Medical Center
RECRUITINGDallas, Texas, 75246, United States
Contact
Contact Email: •••••@•••••
-
Houston Methodist Hospital
RECRUITINGHouston, Texas, 77030, United States
Contact Email: •••••@•••••
Contact
-
LDS Hospital
RECRUITINGSalt Lake City, Utah, 84143, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Mayo Clinic Jacksonville
RECRUITINGJacksonville, Florida, 32224, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Mayo Clinic Rochester
RECRUITINGRochester, Minnesota, 55905, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
Michigan Med University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109 5271, United States
Contact Email: •••••@•••••
Contact
-
Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
Contact
Contact Email: •••••@•••••
-
Novartis Investigative Site
RECRUITINGSalvador, Estado de Bahia, 41253-190, Brazil
-
Novartis Investigative Site
RECRUITINGBarretos, São Paulo, 14784 400, Brazil
-
Novartis Investigative Site
RECRUITINGSão Paulo, São Paulo, 01308-050, Brazil
-
Novartis Investigative Site
RECRUITINGSão Paulo, 01509-010, Brazil
-
Novartis Investigative Site
RECRUITINGHaifa, 3109601, Israel
-
Novartis Investigative Site
RECRUITINGRamat Gan, 5265601, Israel
-
Novartis Investigative Site
RECRUITINGSapporo, Hokkaido, 060-8648, Japan
-
Novartis Investigative Site
RECRUITINGKobe, Hyōgo, 6500047, Japan
-
Novartis Investigative Site
RECRUITINGSendai, Miyagi, 9808574, Japan
-
Novartis Investigative Site
RECRUITINGSuita, Osaka, 565-0871, Japan
-
Novartis Investigative Site
RECRUITINGBunkyo Ku, Tokyo, 1138431, Japan
-
Novartis Investigative Site
RECRUITINGShinjuku-ku, Tokyo, 1608582, Japan
-
Novartis Investigative Site
RECRUITINGChiba, 2608677, Japan
-
Novartis Investigative Site
RECRUITINGFukuoka, 8128582, Japan
-
Novartis Investigative Site
RECRUITINGIshikawa, 9208641, Japan
-
Novartis Investigative Site
RECRUITINGKyoto, 6068507, Japan
-
Novartis Investigative Site
RECRUITINGRiyadh, 11211, Saudi Arabia
-
Novartis Investigative Site
RECRUITINGSingapore, 119074, Singapore
-
Novartis Investigative Site
RECRUITINGSingapore, S308433, Singapore
-
Novartis Investigative Site
RECRUITINGBasel, 4031, Switzerland
-
Novartis Investigative Site
RECRUITINGBern, 3010, Switzerland
-
Novartis Investigative Site
RECRUITINGCambridge, CB2 0QQ, United Kingdom
-
Novartis Investigative Site
RECRUITINGLondon, W12 0HS, United Kingdom
-
Novartis Investigative Site
RECRUITINGManchester, M13 9WL, United Kingdom
-
Oregon Health Sciences University
RECRUITINGPortland, Oregon, 97239, United States
Contact
Contact Email: •••••@•••••
-
University Of Colorado
RECRUITINGAurora, Colorado, 80045, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55455, United States
Contact Email: •••••@•••••
Contact
Conditions
Explore the condition pages connected to this study.