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New Dual-Target CAR-T therapy offers hope for Hard-to-Treat lymphoma

NCT ID NCT05800977

First seen Jan 07, 2026 · Last updated May 23, 2026 · Updated 15 times

Summary

This study tests a new treatment called C-CAR039 (Prizlon-cel) for people with large B-cell lymphoma that has come back or not responded to other treatments. The therapy uses a patient's own immune cells, modified to target two markers on cancer cells (CD19 and CD20). The goal is to find the safest dose and see how well it shrinks tumors. About 112 adults will take part in this early-phase trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Cancer Hospital

    COMPLETED

    Beijing, China

  • Beijing GoBroad Hospital

    RECRUITING

    Beijing, China

    Contact

  • Cancer Hospital of Shandong First Medical University

    RECRUITING

    Jinan, China

    Contact

  • Chinese Academy of Medical Sciences Hematology Hospital

    RECRUITING

    Tianjin, China

    Contact

    Contact

  • Chongqing University Cancer Hospital

    RECRUITING

    Chongqing, China

    Contact

  • Guangdong Provincial People's Hospital

    RECRUITING

    Guangzhou, China

    Contact

  • Henan Cancer Hospital

    RECRUITING

    Zhengzhou, China

    Contact

  • Jiangsu Province Hospital

    RECRUITING

    Nanjing, China

    Contact

  • Jiangxi Cancer Hospital

    RECRUITING

    Nanchang, China

    Contact

  • Peking University Third Hospital

    RECRUITING

    Beijing, China

    Contact

  • Ruijin Hospital, Shanghai Jiaotong University School of Medicine

    RECRUITING

    Shanghai, China

    Contact

  • The First Affiliated Hospital Zhejiang University School of Medicine

    RECRUITING

    Hangzhou, China

    Contact

  • The First Affiliated Hospital of Zhengzhou University

    RECRUITING

    Zhengzhou, China

    Contact

  • Tianjin Medical University Cancer Institute& Hospital

    RECRUITING

    Tianjin, China

    Contact

  • Zhujiang Hospital of Southern Medical University

    RECRUITING

    Guangzhou, China

    Contact

Conditions

Explore the condition pages connected to this study.