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First-in-Human trial tests 'Living Drug' for autoimmune conditions

NCT ID NCT06680037

Summary

This is an early-stage safety study testing a new CAR T-cell therapy called azercabtagene zapreleucel for people with B-cell mediated autoimmune disorders like progressive multiple sclerosis. The main goal is to find the safest and most effective dose for future studies by monitoring side effects in 32 participants. This approach uses genetically modified immune cells to target and potentially control the disease.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • TG Therapeutics Investigational Trial Site

    RECRUITING

    La Jolla, California, 92093, United States

  • TG Therapeutics Investigational Trial Site

    NOT_YET_RECRUITING

    Lexington, Kentucky, 40506, United States

  • TG Therapeutics Investigational Trial Site

    RECRUITING

    Ann Arbor, Michigan, 48019, United States

  • TG Therapeutics Investigational Trial Site

    RECRUITING

    Omaha, Nebraska, 68198, United States

  • TG Therapeutics Investigational Trial Site

    RECRUITING

    New York, New York, 10025, United States

  • TG Therapeutics Investigational Trial Site

    RECRUITING

    Rochester, New York, 14642, United States

  • TG Therapeutics Investigational Trial Site

    RECRUITING

    Cleveland, Ohio, 44195, United States

  • TG Therapeutics Investigational Trial Site

    RECRUITING

    Columbus, Ohio, 43210, United States

Conditions

Explore the condition pages connected to this study.