Scientists test 'Living Drug' to reboot immune system in autoimmune patients

NCT ID NCT06680037

Summary

This is an early-stage study to test the safety and find the right dose of a new cell therapy called azercabtagene zapreleucel (azer-cel) for people with B-cell mediated autoimmune diseases, including progressive forms of multiple sclerosis (MS). The therapy involves modifying a patient's own immune cells (CAR T-cells) to target and reduce harmful B-cells. The main goal is to see how safe the treatment is and to determine the best dose for future, larger studies.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • TG Therapeutics Investigational Trial Site

    RECRUITING

    La Jolla, California, 92093, United States

  • TG Therapeutics Investigational Trial Site

    NOT_YET_RECRUITING

    Lexington, Kentucky, 40506, United States

  • TG Therapeutics Investigational Trial Site

    RECRUITING

    Ann Arbor, Michigan, 48019, United States

  • TG Therapeutics Investigational Trial Site

    RECRUITING

    Omaha, Nebraska, 68198, United States

  • TG Therapeutics Investigational Trial Site

    RECRUITING

    New York, New York, 10025, United States

  • TG Therapeutics Investigational Trial Site

    RECRUITING

    Rochester, New York, 14642, United States

  • TG Therapeutics Investigational Trial Site

    RECRUITING

    Cleveland, Ohio, 44195, United States

  • TG Therapeutics Investigational Trial Site

    RECRUITING

    Columbus, Ohio, 43210, United States

Conditions

Explore the condition pages connected to this study.